The Hyatt Regency Mission Bay Spa and Marina offers a mixed but generally positive experience with a 4.1/5 rating. Recent renovations have improved the rooms, and guests consistently praise the helpful staff and waterfront dining. While the location provides beautiful views and proximity to SeaWorld, it can feel isolated from other attractions. The property features appealing amenities like water slides and marina access, though some areas show signs of aging. High parking fees and occasional understaffing during busy periods are notable drawbacks. Overall, it provides a comfortable stay with strong service, particularly well-suited for families visiting SeaWorld or those seeking a waterfront resort experience.